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Maria Clara e o pai, Spartaco Astolfi, junto com a equipe de pesquisadores da Ufam<\/strong><\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ custom_padding_last_edited=”on|tablet” admin_label=”About” _builder_version=”4.5.1″ width=”92vw” module_alignment=”center” custom_margin=”1px|||||” custom_padding=”|||5vw|false|false” custom_padding_tablet=”|10vw||10vw||true” custom_padding_phone=”” custom_width_px__hover=”1080px” custom_width_px__hover_enabled=”1080px” custom_width_percent__hover=”80%” custom_width_percent__hover_enabled=”80%” gutter_width__hover=”3″ gutter_width__hover_enabled=”3″ parallax_1__hover=”off” parallax_1__hover_enabled=”off” parallax_2__hover=”off” parallax_2__hover_enabled=”off” parallax_3__hover=”off” parallax_3__hover_enabled=”off” parallax_method_1__hover=”on” parallax_method_1__hover_enabled=”on” parallax_method_2__hover=”on” parallax_method_2__hover_enabled=”on” parallax_method_3__hover=”on” 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hover_transition_delay__hover=”0ms” hover_transition_delay__hover_enabled=”0ms” hover_transition_speed_curve__hover=”ease” hover_transition_speed_curve__hover_enabled=”ease”][et_pb_row column_structure=”3_5,2_5″ _builder_version=”3.25″ width=”100%” max_width=”100%” module_alignment=”right” custom_padding=”27px|0px|0|0px|false|false” use_custom_width=”on” width_unit=”off” custom_width_percent=”100%”][et_pb_column type=”3_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding_tablet=”|10vw||10vw||true” custom_padding_phone=”|||” custom_padding_last_edited=”off|desktop” custom_padding__hover=”|||”][et_pb_divider color=”#FFBA5A” divider_weight=”3px” _builder_version=”3.18.2″ max_width=”80px” height=”3px”] \u00c0 primeira vista, como manauara da gema, deixar o tesouro ecol\u00f3gico da Amaz\u00f4nia em troca do sonho em terra ianque seria uma atitude inesperada para quem n\u00e3o apenas ama, mas vive da natureza \u2013 ou melhor, do que tem dentro dela e ningu\u00e9m v\u00ea. Mas por tr\u00e1s dessa hist\u00f3ria h\u00e1 um sen\u00e3o que faz todo sentido. Na cidade de Boston, Estados Unidos, o prop\u00f3sito da bi\u00f3loga Maria Clara Astolfi, 23 anos, \u00e9 preparar-se com muni\u00e7\u00e3o tecnol\u00f3gica de ponta exatamente para conhecer melhor e conservar a floresta que tanto defende. E a estrat\u00e9gia \u00e9 levada a cabo por um meio nada convencional: redesenhando mol\u00e9culas de seres vivos com apoio de intelig\u00eancia artificial e rob\u00f4s para o mercado fazer insumos de novos produtos de sa\u00fade, agricultura e solu\u00e7\u00f5es de energia e alimentos.<\/span><\/p>\n Em troca da oportunidade nos EUA, os planos do mestrado e doutorado, para seguir na carreira acad\u00eamica, foram adiados. Por uma boa causa: a pesquisadora sabe que a mat\u00e9ria-prima biotecnol\u00f3gica da Amaz\u00f4nia, representada pela microfauna de v\u00edrus, bact\u00e9rias, fungos, protozo\u00e1rios e outros organismos, n\u00e3o existiria sem a floresta de p\u00e9. E l\u00e1 fora, conectada ao que h\u00e1 de mais moderno no front<\/em>, as chances de dominar as armas da biologia sint\u00e9tica para vencer essa batalha s\u00e3o bem maiores.<\/span><\/p>\n No caso de Maria Clara, o apre\u00e7o pela natureza vai al\u00e9m da beleza da floresta, dos banhos de rio ou do conv\u00edvio com popula\u00e7\u00f5es tradicionais \u2013 como \u00e9 para muitos que se aventuram na Amaz\u00f4nia. O interesse da bi\u00f3loga est\u00e1 no mundo desconhecido por entre \u00e1rvores e igarap\u00e9s, alvo de tecnologias que debulham c\u00f3digos da vida, campo do conhecimento que a cativa desde os tempos do Ensino M\u00e9dio, em 2012, quando iniciou est\u00e1gio na Universidade Federal do Amazonas (Ufam). N\u00e3o faltou incentivo do pai, o pesquisador Spartaco Astolfi, pioneiro na forma\u00e7\u00e3o de pesquisadores na regi\u00e3o (leia na reportagem \u201cA riqueza oculta da floresta\u201d, nesta plataforma<\/em>).<\/span><\/p>\n Em Manaus, a bi\u00f3loga desenhou mol\u00e9culas produtoras de prote\u00ednas de uso farmac\u00eautico, com pedido de patente, mas a velocidade da tecnologia no mundo a fez arrumar as malas para voar mais longe: \u201cEmpresas mais inovadoras do mundo j\u00e1 usavam biologia como m\u00e9todo de manufatura\u201d.<\/span><\/p>\n O plano de estabelecer trincheira acima da Linha do Equador se mostrava promissor, a contar pela estirpe do lugar que a acolheu: a Ginkgo Bioworks, startup unic\u00f3rnio de US$ 7 bilh\u00f5es, uma das mais famosas do mundo em bioengenharia, com sede em Boston e equipe de 400 millenials <\/em>especializados na automa\u00e7\u00e3o de design e delivery de microrganismo para diferentes mercados.<\/span><\/p>\n O passaporte de Maria Clara para a transfer\u00eancia foi a medalha de prata conquistada, em 2017, no desafio global The International Genetically Engineered Machine Competition (iGEM), criada pelo Instituto de Tecnologia de Massachusetts, nos EUA, reunindo jovens pesquisadores \u00e0 frente de inova\u00e7\u00f5es biotecnol\u00f3gicas que solucionam problemas regionais. A equipe de Manaus concorreu com uma nov\u00edssima tecnologia de edi\u00e7\u00e3o gen\u00f4mica, desenvolvida pela Ufam com base no que j\u00e1 existia em pa\u00edses mais avan\u00e7ados \u2013 ferramenta capaz de tornar a engenharia de mol\u00e9culas mais f\u00e1cil e acess\u00edvel a laborat\u00f3rios de pesquisa brasileiros.<\/span><\/p>\n No evento da competi\u00e7\u00e3o, um dos fundadores da empresa americana, Tom Knight, assistiu \u00e0 apresenta\u00e7\u00e3o da brasileira e a convidou para enviar o curr\u00edculo e possivelmente fazer parte da equipe, ap\u00f3s se formar na universidade em Manaus. \u201cEle ficou fascinado por termos criado um n\u00facleo de biologia sint\u00e9tica na Amaz\u00f4nia, aproveitando o potencial da regi\u00e3o\u201d, diz a pesquisadora.<\/span><\/p>\n N\u00e3o foi a primeira vez que Maria Clara frequentou aquela competi\u00e7\u00e3o internacional. Em 2014, recebeu ouro pela tecnologia de biossensores, desenvolvida na universidade amazonense com bact\u00e9rias que tiveram o c\u00f3digo gen\u00e9tico reprogramado para emitir um sinal luminoso verde quando em contato com o merc\u00fario, liberado por garimpos em rios da Amaz\u00f4nia. Al\u00e9m de detectar o poluente, o microrganismo \u00e9 capaz de degrad\u00e1-lo no ambiente, o que inspirou outros projetos para tratamento de \u00e1gua e testes para aumento de escala dos resultados na Ufam.<\/span><\/p>\n \u201cA trajet\u00f3ria nas novas tecnologias n\u00e3o tinha mais volta\u201d, ressalta Maria Clara, que antes de decolar para Boston concluiu uma nova pesquisa baseada em microrganismo da Amaz\u00f4nia: o sequenciamento gen\u00e9tico de bact\u00e9ria isolada de um igarap\u00e9 da regi\u00e3o \u2013 a Enterobacter amazonenses<\/em>, que pode potencialmente se somar a estrat\u00e9gias de tratamento de efluentes.<\/p>\n <\/p>\n Na startup <\/em>americana, a bi\u00f3loga acompanha projetos que aplicam rob\u00f4s e intelig\u00eancia artificial para automatizar a engenharia molecular, viabilizando produtos inovadores. Um dos exemplos \u00e9 a carne vegana fabricada em laborat\u00f3rio por microrganismos que reproduzem as mol\u00e9culas (prote\u00ednas) presentes no produto de origem animal. Neste caso, diferentemente dos similares j\u00e1 existentes no mercado, obt\u00e9m-se igual consist\u00eancia e textura \u2013 sem adi\u00e7\u00e3o de soja. \u201cA meta \u00e9 fazer o mesmo com ovos, leite e outras carnes para aumentar o portf\u00f3lio de produtos veganos \u00e0 popula\u00e7\u00e3o\u201d, revela Maria Clara.<\/span><\/p>\n A ideia, segundo ela, \u00e9 conviver alguns anos com esse intenso ambiente de novas tecnologias e lev\u00e1-las para a Amaz\u00f4nia. \u201cMas, para isso, o Pa\u00eds precisa rever caminhos e investir mais em ci\u00eancia e tecnologia\u201d, observa a bi\u00f3loga, desde o apartamento de Boston, onde vive ao lado de outros jovens pesquisadores garimpados pela empresa no mundo. Nas paredes, quadros de arte ind\u00edgena dividem espa\u00e7o com pinturas que lembram c\u00e9lulas humanas. Tudo a ver quando o tema da conversa \u00e9 biotecnologia amaz\u00f4nica.<\/span><\/p>\n \u201cQuando assistem ao desmatamento e queimadas pela televis\u00e3o, as pessoas aqui n\u00e3o entendem como o Brasil \u00e9 grande fornecedor de produtos agr\u00edcolas e etanol da cana e n\u00e3o aproveita a biodiversidade da Amaz\u00f4nia\u201d, completa Maria Clara. Al\u00e9m do cabelo esverdeado nas pontas, a f\u00e3 do Boi Caprichoso carrega no estilo vistosos brincos de semente de a\u00e7a\u00ed e palha de buriti. S\u00e3o pequenas amostras levadas da terrinha e usadas quase como um alento na \u201cdificuldade de explicar porque temos s\u00f3 potencial e n\u00e3o produtos\u201d.<\/span><\/p>\n [\/et_pb_text][\/et_pb_column][et_pb_column type=”2_5″ _builder_version=”3.25″ custom_padding=”|||” custom_padding_tablet=”0vw|||” custom_padding_phone=”|||” custom_padding_last_edited=”off|desktop” custom_padding__hover=”|||”][et_pb_image src=”https:\/\/pagina22.com.br\/bioeconomia-solucoes-covid-19\/wp-content\/uploads\/2020\/08\/02_perfil_interna.jpeg” alt=”A imagem mostra a\u00e7\u00e3o de bact\u00e9ria selecionada na natureza contra fungos que atacam culturas agr\u00edcolas.” title_text=”02_perfil_interna” _builder_version=”4.5.1″ _module_preset=”default”][\/et_pb_image][et_pb_text _builder_version=”4.5.1″ _module_preset=”default” text_font=”|700|||||||” min_height=”24px” custom_padding=”||2px|||”]<\/p>\n Biossensores de bact\u00e9rias detectam a presen\u00e7a de contaminantes pela cor<\/p>\n [\/et_pb_text][et_pb_divider _builder_version=”4.5.1″ _module_preset=”default”][\/et_pb_divider][et_pb_image src=”https:\/\/pagina22.com.br\/bioeconomia-solucoes-covid-19\/wp-content\/uploads\/2020\/08\/03_perfil_interna.jpg” alt=”A mastruz \u00e9 pesquisada na Ufam pelo potencial contra o novo cororonav\u00edrus.” title_text=”03_perfil_interna” _builder_version=”4.5.1″ _module_preset=”default” custom_padding=”1px|||||”][\/et_pb_image][et_pb_text _builder_version=”4.5.1″ _module_preset=”default” text_font=”|700|||||||” custom_padding=”||1px|||”]<\/p>\n Genoma sequenciado da nova linhagem de bact\u00e9ria <\/span>Enterobacter amazonensis<\/i>, na Ufam. Foi obtida de um igarap\u00e9 da Amaz\u00f4nia e \u00e9 altamente resistente a metais pesados, podendo ser utilizada como tecnologia para biorremedi\u00e7\u00e3o de contaminantes nos rios<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" [et_pb_section fb_built=”1″ custom_padding_last_edited=”on|phone” admin_label=”Header” _builder_version=”4.5.1″ use_background_color_gradient=”on” background_color_gradient_start=”rgba(165,206,199,0.32)” background_color_gradient_end=”#151f33″ background_color_gradient_overlays_image=”on” background_image=”https:\/\/pagina22.com.br\/bioeconomia-solucoes-covid-19\/wp-content\/uploads\/2020\/08\/01_perfil_interna-1.jpeg” background_position=”top_center” width=”96vw” module_alignment=”center” custom_margin=”2vw||||false|false” custom_padding=”10vw||0px||false|false” custom_padding_tablet=”20%||||false|false” custom_padding_phone=”” background_color_gradient_start__hover=”#2b87da” background_color_gradient_start__hover_enabled=”#2b87da” background_color_gradient_end__hover=”#29c4a9″ background_color_gradient_end__hover_enabled=”#29c4a9″ use_background_color_gradient__hover=”off” use_background_color_gradient__hover_enabled=”off” background_color_gradient_type__hover=”linear” background_color_gradient_type__hover_enabled=”linear” background_color_gradient_direction__hover=”180deg” background_color_gradient_direction__hover_enabled=”180deg” background_color_gradient_direction_radial__hover=”center” background_color_gradient_direction_radial__hover_enabled=”center” background_color_gradient_start_position__hover=”0%” background_color_gradient_start_position__hover_enabled=”0%” background_color_gradient_end_position__hover=”100%” background_color_gradient_end_position__hover_enabled=”100%” background_color_gradient_overlays_image__hover=”off” background_color_gradient_overlays_image__hover_enabled=”off”][et_pb_row _builder_version=”3.25″ max_width=”80%” use_custom_width=”on” width_unit=”off” custom_width_px__hover=”1080px” custom_width_px__hover_enabled=”1080px” custom_width_percent__hover=”80%” custom_width_percent__hover_enabled=”80%” gutter_width__hover=”3″ gutter_width__hover_enabled=”3″ parallax_1__hover=”off” parallax_1__hover_enabled=”off” parallax_2__hover=”off” parallax_2__hover_enabled=”off” parallax_3__hover=”off” parallax_3__hover_enabled=”off” parallax_4__hover=”off” parallax_4__hover_enabled=”off” parallax_5__hover=”off” parallax_5__hover_enabled=”off” […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"2880","footnotes":""},"categories":[1],"tags":[],"class_list":["post-250","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/pagina22.com.br\/bioeconomia-solucoes-covid-19\/wp-json\/wp\/v2\/posts\/250","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pagina22.com.br\/bioeconomia-solucoes-covid-19\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pagina22.com.br\/bioeconomia-solucoes-covid-19\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pagina22.com.br\/bioeconomia-solucoes-covid-19\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pagina22.com.br\/bioeconomia-solucoes-covid-19\/wp-json\/wp\/v2\/comments?post=250"}],"version-history":[{"count":10,"href":"https:\/\/pagina22.com.br\/bioeconomia-solucoes-covid-19\/wp-json\/wp\/v2\/posts\/250\/revisions"}],"predecessor-version":[{"id":491,"href":"https:\/\/pagina22.com.br\/bioeconomia-solucoes-covid-19\/wp-json\/wp\/v2\/posts\/250\/revisions\/491"}],"wp:attachment":[{"href":"https:\/\/pagina22.com.br\/bioeconomia-solucoes-covid-19\/wp-json\/wp\/v2\/media?parent=250"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pagina22.com.br\/bioeconomia-solucoes-covid-19\/wp-json\/wp\/v2\/categories?post=250"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pagina22.com.br\/bioeconomia-solucoes-covid-19\/wp-json\/wp\/v2\/tags?post=250"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\n[\/et_pb_divider][et_pb_text _builder_version=”4.5.1″ text_font=”||||||||” text_font_size=”16px” text_line_height=”2em” header_2_font=”||||||||” text_font_size_tablet=”14px” text_font_size_phone=”” text_font_size_last_edited=”on|phone”]<\/p>\nCarne vegana em laborat\u00f3rio<\/span><\/strong><\/h4>\n